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Megamind (Will Ferrell) and his life-long archenemy Metro Man (Brad Pitt) are aliens that were sent away from their respective home planets in time of crisis (much like Superman's origin story), with Metro Man ending up in a loving home and Megamind landing in the local prison. Megamind, taking the role of super villain, tries to conquer Metro City in every imaginable way, each attempt a colossal failure thanks to Metro Man, who becomes known as the city's hero. It seems that the pattern will never cease until Megamind seemingly defeats Metro Man during one of his many botched hostage plots involving news reporter Roxanne Ritchi (Tina Fey). Now freed from his rival's shadow, Megamind proceeds to take control of Metro City. Over time, Megamind comes to the realization that he no longer has any purpose in life without an enemy. To appease his depression, he turns Roxanne's lonely cameraman Hal (Jonah Hill) into Metro City's next big superhero, the fiery-headed Titan. Unfortunately for Megamind, Titan decides to utilize his new power against humanity as revenge for the lifetime of rejection he has endured. When Metro Man is discovered alive by Megamind and Roxanne, but uninterested in resuming his superhero duties, Megamind is forced to do the inevitable: become the hero of the crisis. Aided by his childhood, fish-like sidekick Minion (David Cross), Megamind now sets out to stop Titan's rampage of destruction, thus beginning a path to redemption.
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